Webinar: Endotoxin: Control, Analysis and Clinical Relevance


Endotoxin is ubiquitous, it’s in the soil, the air and water that we encounter every day of our lives. Normally it presents no problem to us, but if it should enter our bloodstream it can be the very worst news possible. The control of water systems within hemodialysis centres is therefore of critical importance, to the facility in general, but more so to the patients treated at the facility. This presentation will endeavour to further the understanding of the harmful effects of endotoxin and how to control it through simple, rapid, quantitative testing.

Learning Objectives

  • What is endotoxin and why is it important to test for it.
  • The importance of reliable data and data integrity.
  • How to test for endotoxins using a simple, rapid quantitative test method.

Date and Time

March 11, 2021 at 11:00 AM – 12:00 PM ET


Alan Hoffmeister is the Senior Global Technology & Market Development Manager for the Microbial Solutions division of Charles River Laboratories. His experience with the bacterial endotoxins test dates back to 1988, during which time he has been involved in all aspects of the assay, including the design and development of BET-specific instrumentation and software.

He has directed workshops and training courses and lectured internationally on a variety of BET-related topics, including LAL methodologies, system qualification, product validations, 21 CFR Part 11, process analytical technologies (PAT) and BET regulatory affairs. He has also contributed to the development of many BET protocols, technical sheets and monographs for domestic and international organizations.

Jordi Iglesias is a biologist with a specialty in Biotechnology by the Barcelona University. Currently, he is part of the Charles River –Microbial solutions team as a technology and market development manager for Endosafe brand (endotoxin testing) in Europe and supporting also Spanish speaking regions. His previous experience was in the pharmaceutical industry as Aseptic and Microbiology lab Manager for almost 15 years. During these years I designed product validations (bioburden, sterility and endotoxins), environmental monitoring plans, cleaning and disinfection programs, training for aseptic areas operators and part of the human performance (human error assessment) group. Jordi Iglesias is also a EDQM (European directorate for quality of medicines) member for the Microbiology group.

George currently lives in Calgary, Alberta with his family. He is a graduate of the Faculty of Medicine, Cell Biology at the University of Alberta, Edmonton with a focus on Breast Cancer Protein Signaling. He conducted several years of Medical Science research in the fields of Cell Receptor biology and Primary Cell Neurobiology prior to adventuring into the business of science. Currently George has over 15 years in Business Development and successful Strategic Sales in the Organic Chemistry, Molecular Biology, Lifesciences and Analytical Sciences industries. He joined the Charles River Laboratories – Microbial Solutions division in 2019 as an Account Manager, establishing relationships and being a resourceful solutions provider with expertise in the Canadian Biotech and Biopharma sectors from British Columbia to the Maritimes. He is an avid outdoorsman, sharing his love for photography, cycling and hiking with family, friends and his 2-year-old Lagotto Romagnolo. He is a passionate student of the Culinary Arts and a self proclaimed foodie.

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